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Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia

Schizophrenia patients exhibit increased hippocampal activity that is correlated with positive symptoms. While the cause of this hippocampal hyperactivity has not been demonstrated, it likely involves a decrease in GABAergic signaling. Thus, we posit that restoring GABAergic function may provide a n...

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Detalhes bibliográficos
Main Authors: Perez, Stephanie M., Lodge, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028118/
https://ncbi.nlm.nih.gov/pubmed/23979606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.111
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