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Jumonji Represses Atrial Natriuretic Factor Gene Expression by Inhibiting Transcriptional Activities of Cardiac Transcription Factors

Mice with a homozygous knockout of the jumonji (jmj) gene showed abnormal heart development and defective regulation of cardiac-specific genes, including the atrial natriuretic factor (ANF). ANF is one of the earliest markers of cardiac differentiation and a hallmark for cardiac hypertrophy. Here, w...

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Autors principals: Kim, Tae-gyun, Chen, Junqin, Sadoshima, Junich, Lee, Youngsook
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC529025/
https://ncbi.nlm.nih.gov/pubmed/15542826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10151-10160.2004
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