Proinflammatory cytokine interferon‐γ and microbiome‐derived metabolites dictate epigenetic switch between forkhead box protein 3 isoforms in coeliac disease

Coeliac disease (CD) is an autoimmune enteropathy triggered by gluten and characterized by a strong T helper type 1 (Th1)/Th17 immune response in the small intestine. Regulatory T cells (T(reg)) are CD4(+)CD25(++)forkhead box protein 3 (FoxP3(+)) cells that regulate the immune response. Conversely t...

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發表在:Clin Exp Immunol
Main Authors: Serena, G., Yan, S., Camhi, S., Patel, S., Lima, R. S., Sapone, A., Leonard, M. M., Mukherjee, R., Nath, B. J., Lammers, K. M., Fasano, A.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290237/
https://ncbi.nlm.nih.gov/pubmed/27936497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12911
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