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Proinflammatory cytokine interferon‐γ and microbiome‐derived metabolites dictate epigenetic switch between forkhead box protein 3 isoforms in coeliac disease
Coeliac disease (CD) is an autoimmune enteropathy triggered by gluten and characterized by a strong T helper type 1 (Th1)/Th17 immune response in the small intestine. Regulatory T cells (T(reg)) are CD4(+)CD25(++)forkhead box protein 3 (FoxP3(+)) cells that regulate the immune response. Conversely t...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5290237/ https://ncbi.nlm.nih.gov/pubmed/27936497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12911 |
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