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Proapoptotic Function of the MET Tyrosine Kinase Receptor through Caspase Cleavage

The MET tyrosine kinase, the receptor of hepatocyte growth factor-scatter factor (HGF/SF), is known to be essential for normal development and cell survival. We report that stress stimuli induce the caspase-mediated cleavage of MET in physiological cellular targets, such as epithelial cells, embryon...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Tulasne, David, Deheuninck, Julien, Lourenc̨o, Filipe Calheiros, Lamballe, Fabienne, Ji, Zongling, Leroy, Catherine, Puchois, Emilie, Moumen, Anice, Maina, Flavio, Mehlen, Patrick, Fafeur, Véronique
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542841/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.23.10328-10339.2004
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