Proapoptotic Function of the MET Tyrosine Kinase Receptor through Caspase Cleavage

The MET tyrosine kinase, the receptor of hepatocyte growth factor-scatter factor (HGF/SF), is known to be essential for normal development and cell survival. We report that stress stimuli induce the caspase-mediated cleavage of MET in physiological cellular targets, such as epithelial cells, embryon...

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Detalles Bibliográficos
Autores principales: Tulasne, David, Deheuninck, Julien, Lourenc̨o, Filipe Calheiros, Lamballe, Fabienne, Ji, Zongling, Leroy, Catherine, Puchois, Emilie, Moumen, Anice, Maina, Flavio, Mehlen, Patrick, Fafeur, Véronique
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC529022/
https://ncbi.nlm.nih.gov/pubmed/15542841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10328-10339.2004
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