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α3β1 Integrin suppresses prostate cancer metastasis via regulation of the Hippo pathway

Existing anti-cancer strategies focused on disrupting integrin functions in tumor cells or tumor-involved endothelial cells have met limited success. An alternative strategy is to augment integrin-mediated pathways that suppress tumor progression, but how integrins can signal to restrain malignant b...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Varzavand, Afshin, Hacker, Will, Ma, Deqin, Gibson-Corley, Katherine, Hawayek, Maria, Tayh, Omar J., Brown, James A., Henry, Michael D., Stipp, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290210/
https://ncbi.nlm.nih.gov/pubmed/27680681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1483
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