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INTEGRIN α3β1 REGULATES TUMOR CELL RESPONSES TO STROMAL CELLS AND CAN FUNCTION TO SUPPRESS PROSTATE CANCER METASTATIC COLONIZATION

Integrin α3β1 promotes tumor cell adhesion, migration, and invasion on laminin isoforms, and several clinical studies have indicated a correlation between increased tumoral α3β1 integrin expression and tumor progression, metastasis, and poor patient outcomes. However, several other clinical and expe...

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Detalhes bibliográficos
Main Authors: Varzavand, Afshin, Drake, Justin M., Svensson, Robert U., Herndon, Mary E., Zhou, Bo, Henry, Michael D., Stipp, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604149/
https://ncbi.nlm.nih.gov/pubmed/23224938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-012-9558-1
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