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BRD4 regulates breast cancer dissemination through Jagged1/Notch1 signaling

The Bromodomain and ExtraTerminal (BET) proteins are epigenetic ‘readers’ of acetylated histones in chromatin and have been identified as promising therapeutic targets in diverse cancers. However, it remains unclear how individual family members participate in cancer progression, and small molecule...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Andrieu, Guillaume, Tran, Anna H., Strissel, Katherine J., Denis, Gerald V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290198/
https://ncbi.nlm.nih.gov/pubmed/27651315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0559
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