A HETEROZYGOUS MUTATION IN TUBULIN, BETA 2B (TUBB2B) CAUSES COGNITIVE DEFICITS AND HIPPOCAMPAL DISORGANIZATION

Development of the mammalian forebrain requires a significant contribution from tubulin proteins to physically facilitate both the large number of mitoses in the neurogenic brain (in the form of mitotic spindles) as well as support cellular scaffolds to guide radial migration (radial glial neuroblas...

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Pubblicato in:Genes Brain Behav
Autori principali: Stottmann, Rolf W., Driver, Ashley, Gutierrez, Arnold, Skelton, Matthew R., Muntifering, Michael, Stepien, Christopher, Knudson, Luke, Kofron, Matthew, Vorhees, Charles V., Williams, Michael T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290086/
https://ncbi.nlm.nih.gov/pubmed/27594048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12327
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