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Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1

Benzimidazole derivatives of 5,6-dichlorobenzimidazole 1-β-d-ribofuranoside (DRB) comprise the important class of protein kinase CK2 inhibitors. Depending on the structure, benzimidazoles inhibit CK2 with different selectivity and potency. Besides CK2, the compounds can inhibit, with similar activit...

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Detalhes bibliográficos
Publicado no:Mol Cell Biochem
Main Authors: Kubiński, Konrad, Masłyk, Maciej, Orzeszko, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290066/
https://ncbi.nlm.nih.gov/pubmed/27909846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-016-2892-x
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