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Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1

Benzimidazole derivatives of 5,6-dichlorobenzimidazole 1-β-d-ribofuranoside (DRB) comprise the important class of protein kinase CK2 inhibitors. Depending on the structure, benzimidazoles inhibit CK2 with different selectivity and potency. Besides CK2, the compounds can inhibit, with similar activit...

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Bibliografski detalji
Izdano u:Mol Cell Biochem
Glavni autori: Kubiński, Konrad, Masłyk, Maciej, Orzeszko, Andrzej
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290066/
https://ncbi.nlm.nih.gov/pubmed/27909846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-016-2892-x
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