Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation

Tumor-associated lymphatic vessels (LVs) play multiple roles during tumor progression, including promotion of metastasis and regulation of antitumor immune responses by delivering antigen from the tumor bed to draining lymph nodes (LNs). Under steady-state conditions, LN resident lymphatic endotheli...

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Udgivet i:Front Immunol
Main Authors: Dieterich, Lothar C., Ikenberg, Kristian, Cetintas, Timur, Kapaklikaya, Kübra, Hutmacher, Cornelia, Detmar, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289955/
https://ncbi.nlm.nih.gov/pubmed/28217128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00066
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