Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation

Tumor-associated lymphatic vessels (LVs) play multiple roles during tumor progression, including promotion of metastasis and regulation of antitumor immune responses by delivering antigen from the tumor bed to draining lymph nodes (LNs). Under steady-state conditions, LN resident lymphatic endotheli...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Dieterich, Lothar C., Ikenberg, Kristian, Cetintas, Timur, Kapaklikaya, Kübra, Hutmacher, Cornelia, Detmar, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289955/
https://ncbi.nlm.nih.gov/pubmed/28217128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00066
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