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Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation

Tumor-associated lymphatic vessels (LVs) play multiple roles during tumor progression, including promotion of metastasis and regulation of antitumor immune responses by delivering antigen from the tumor bed to draining lymph nodes (LNs). Under steady-state conditions, LN resident lymphatic endotheli...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Dieterich, Lothar C., Ikenberg, Kristian, Cetintas, Timur, Kapaklikaya, Kübra, Hutmacher, Cornelia, Detmar, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289955/
https://ncbi.nlm.nih.gov/pubmed/28217128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00066
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