RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

Histone methylation is a dynamic and reversible process proposed to directly impact on stem cell fate. The Jumonji (JmjC) domain–containing family of demethylases comprises 27 members that target mono-, di-, and trimethylated lysine residues of histone (or nonhistone) proteins. To evaluate their rol...

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Pubblicato in:Blood
Autori principali: Cellot, Sonia, Hope, Kristin J., Chagraoui, Jalila, Sauvageau, Martin, Deneault, Éric, MacRae, Tara, Mayotte, Nadine, Wilhelm, Brian T., Landry, Josette R., Ting, Stephen B., Krosl, Jana, Humphries, Keith, Thompson, Alexander, Sauvageau, Guy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289888/
https://ncbi.nlm.nih.gov/pubmed/23777767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-496281
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