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Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in ageing societies, triggered by both environmental and genetic factors. The strongest genetic signal for AMD with odds ratios of up to 2.8 per adverse allele was found previously over a chromosomal region in 10q26 harboring t...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Grassmann, Felix, Heid, Iris M., Weber, Bernhard H. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289859/
https://ncbi.nlm.nih.gov/pubmed/27879347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.195966
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