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Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in ageing societies, triggered by both environmental and genetic factors. The strongest genetic signal for AMD with odds ratios of up to 2.8 per adverse allele was found previously over a chromosomal region in 10q26 harboring t...

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書目詳細資料
發表在:Genetics
Main Authors: Grassmann, Felix, Heid, Iris M., Weber, Bernhard H. F.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289859/
https://ncbi.nlm.nih.gov/pubmed/27879347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.195966
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