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Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in ageing societies, triggered by both environmental and genetic factors. The strongest genetic signal for AMD with odds ratios of up to 2.8 per adverse allele was found previously over a chromosomal region in 10q26 harboring t...

詳細記述

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書誌詳細
出版年:Genetics
主要な著者: Grassmann, Felix, Heid, Iris M., Weber, Bernhard H. F.
フォーマット: Artigo
言語:Inglês
出版事項: Genetics Society of America 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289859/
https://ncbi.nlm.nih.gov/pubmed/27879347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.195966
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