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No neuronal loss, but alterations of the GDNF system in asymptomatic diverticulosis

BACKGROUND: Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor known to promote the survival and maintenance of neurons not only in the developing but also in the adult enteric nervous system. As diverticular disease (DD) is associated with reduced myenteric neurons,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Barrenschee, Martina, Wedel, Thilo, Lange, Christina, Hohmeier, Ines, Cossais, François, Ebsen, Michael, Vogel, Ilka, Böttner, Martina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289619/
https://ncbi.nlm.nih.gov/pubmed/28152033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171416
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