The GDNF System Is Altered in Diverticular Disease – Implications for Pathogenesis

BACKGROUND & AIMS: Absence of glial cell line-derived neurotrophic factor (GDNF) leads to intestinal aganglionosis. We recently demonstrated that patients with diverticular disease (DD) exhibit hypoganglionosis suggesting neurotrophic factor deprivation. Thus, we screened mRNA expression pattern...

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Main Authors: Böttner, Martina, Barrenschee, Martina, Hellwig, Ines, Harde, Jonas, Egberts, Jan-Hendrik, Becker, Thomas, Zorenkov, Dimitri, Schäfer, Karl-Herbert, Wedel, Thilo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689736/
https://ncbi.nlm.nih.gov/pubmed/23805210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066290
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