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PD-L1 Detection in Tumors Using [(64)Cu]Atezolizumab with PET

The programmed death protein 1 (PD-1) and programmed deathligand 1 (PD-L1) pair is a major immune checkpoint pathway exploited by cancer cells to develop and maintain immune tolerance. With recent approvals of anti-PD-1 and anti-PD-L1 therapeutic antibodies, there is an urgent need for noninvasive d...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Lesniak, Wojciech G., Chatterjee, Samit, Gabrielson, Matthew, Lisok, Ala, Wharram, Bryan, Pomper, Martin G., Nimmagadda, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289227/
https://ncbi.nlm.nih.gov/pubmed/27458027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00348
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