A humanized antibody for imaging immune checkpoint ligand PD-L1 expression in tumors

Antibodies targeting the PD-1/PD-L1 immune checkpoint lead to tumor regression and improved survival in several cancers. PD-L1 expression in tumors may be predictive of response to checkpoint blockade therapy. Because tissue samples might not always be available to guide therapy, we developed and ev...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Chatterjee, Samit, Lesniak, Wojciech G., Gabrielson, Matthew, Lisok, Ala, Wharram, Bryan, Sysa-Shah, Polina, Azad, Babak Behnam, Pomper, Martin G., Nimmagadda, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891115/
https://ncbi.nlm.nih.gov/pubmed/26848870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7143
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