TP53 mutation-mediated genomic instability induces the evolution of chemoresistance and recurrence in epithelial ovarian cancer

BACKGROUND: Genomic instability caused by mutation of the checkpoint molecule TP53 may endow cancer cells with the ability to undergo genomic evolution to survive stress and treatment. We attempted to gain insight into the potential contribution of ovarian cancer genomic instability resulted from TP...

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Udgivet i:Diagn Pathol
Main Authors: Zhang, Meiying, Zhuang, Guanglei, Sun, Xiangjun, Shen, Yanying, Wang, Wenjing, Li, Qing, Di, Wen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288946/
https://ncbi.nlm.nih.gov/pubmed/28148293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-017-0605-8
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