Influence of Genetic Polymorphisms in Prostaglandin E2 Pathway (COX-2/HPGD/SLCO2A1/ABCC4) on the Risk for Colorectal Adenoma Development and Recurrence after Polypectomy

OBJECTIVES: Deregulation of prostaglandin E(2) (PGE(2)) levels reported in colorectal carcinogenesis contributes to key steps of cancer development. Our aim was to evaluate the influence of the genetic variability in COX-2/HPGD/SLCO2A1/ABCC4 PGE(2) pathway genes on the development and recurrence of...

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Опубликовано в: :Clin Transl Gastroenterol
Главные авторы: Pereira, Carina, Queirós, Sara, Galaghar, Ana, Sousa, Hugo, Marcos-Pinto, Ricardo, Pimentel-Nunes, Pedro, Brandão, Catarina, Medeiros, Rui, Dinis-Ribeiro, Mário
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Original Contributions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288593/
https://ncbi.nlm.nih.gov/pubmed/27628421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2016.47
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