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Altered expression of ARP2/3 complex signaling pathway genes in prefrontal layer 3 pyramidal cells in schizophrenia

OBJECTIVE: Lower dendritic spine density on layer 3 pyramidal cells in the dorsolateral prefrontal cortex (DLPFC) appears to contribute to cognitive dysfunction in schizophrenia, whereas psychosis is associated with excessive dopamine release in the striatum. These findings might be related via exci...

詳細記述

保存先:
書誌詳細
出版年:Am J Psychiatry
主要な著者: Datta, Dibyadeep, Arion, Dominique, Roman, Kaitlyn M., Volk, David W., Lewis, David A.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288270/
https://ncbi.nlm.nih.gov/pubmed/27523502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2016.16020204
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