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Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder

Schizophrenia is associated with alterations in working memory that reflect dysfunction of dorsolateral prefrontal cortex (DLPFC) circuitry. Working memory depends on the activity of excitatory pyramidal cells in DLPFC layer 3, and to a lesser extent in layer 5. Although many studies have profiled g...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Arion, Dominique, Corradi, John P., Tang, Shaowu, Datta, Dibyadeep, Boothe, Franklyn, He, Aiqing, Cacace, Angela M., Zaczek, Robert, Albright, Charles F., Tseng, George, Lewis, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492919/
https://ncbi.nlm.nih.gov/pubmed/25560755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2014.171
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