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A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals.

A panel of human monoclonal antibody Fab fragments has been generated against the surface glycoprotein gp120 of type 1 human immunodeficiency virus (HIV) by antigen selection from a random combinatorial library expressed on the surface of filamentous phage. The library was prepared from 5 ml of bone...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Burton, D R, Barbas, C F, Persson, M A, Koenig, S, Chanock, R M, Lerner, R A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52882/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1719545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.10134
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