Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion

The actin-binding protein, gelsolin, is a well known regulator of cancer cell invasion. However, the mechanisms by which gelsolin promotes invasion are not well established. As reactive oxygen species (ROS) have been shown to promote cancer cell invasion, we investigated on the hypothesis that gelso...

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Vydáno v:Oncotarget
Hlavní autoři: Tochhawng, Lalchhandami, Deng, Shuo, Pugalenthi, Ganesan, Kumar, Alan Prem, Lim, Kiat Hon, Tan, Tuan Zea, Yang, Henry, Hooi, Shing Chuan, Goh, Yaw Chong, Maciver, Sutherland K., Pervaiz, Shazib, Yap, Celestial T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper: Autophagy and Cell Death
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288152/
https://ncbi.nlm.nih.gov/pubmed/27391159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10451
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