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p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression
SV40 large T-antigen (T-ag) has been known for decades to inactivate the tumor suppressor p53 by sequestration and additional mechanisms. Our present study revealed that the struggle between p53 and T-ag begins very early in the infection cycle. We found that p53 is activated early after SV40 infect...
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| Izdano u: | Oncotarget |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Impact Journals LLC
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5288138/ https://ncbi.nlm.nih.gov/pubmed/27462916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10769 |
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