Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy

DNA is the well-known molecular target of current platinum-based anticancer drugs; consequently, their clinical use is severely restricted by their systemic toxicities and drug resistance originating from non-selective DNA damage. Various strategies have been developed to circumvent the shortcomings...

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Veröffentlicht in:Biochem Pharmacol
Hauptverfasser: Zhao, Chong, Chen, Xin, Zang, Dan, Lan, Xiaoying, Liao, Siyan, Yang, Changshan, Zhang, Peiquan, Wu, Jinjie, Li, Xiaofen, Liu, Ningning, Liao, Yuning, Huang, Hongbiao, Shi, Xianping, Jiang, Lili, Liu, Xiuhua, He, Zhimin, Wang, Xuejun, Liu, Jinbao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287571/
https://ncbi.nlm.nih.gov/pubmed/27381943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.06.019
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