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Sir2 mediates longevity in the fly through a pathway related to calorie restriction
Calorie restriction can extend life span in a variety of species including mammals, flies, nematodes, and yeast. Despite the importance of this nearly universal effect, little is understood about the molecular mechanisms that mediate the life-span-extending effect of calorie restriction in metazoans...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC528752/ https://ncbi.nlm.nih.gov/pubmed/15520384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404184101 |
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