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Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling

Although interactions between superoxide ([Formula: see text]) and nitric oxide underlie many physiologic and pathophysiologic processes, regulation of this crosstalk at the enzymatic level is poorly understood. Here, we demonstrate that xanthine oxidoreductase (XOR), a prototypic superoxide [Formul...

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Autori principali: Khan, Shakil A., Lee, Kwangho, Minhas, Khalid M., Gonzalez, Daniel R., Raju, Shubha V. Y., Tejani, Ankit D., Li, Dechun, Berkowitz, Dan E., Hare, Joshua M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC528749/
https://ncbi.nlm.nih.gov/pubmed/15486091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404136101
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