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Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus
Aspartate-semialdehyde dehydrogenase (ASADH) functions at a critical junction in the aspartate biosynthetic pathway and represents a validated target for antimicrobial drug design. This enzyme catalyzes the NADPH-dependent reductive dephosphorylation of β-aspartyl phosphate to produce the key interm...
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| Publicado no: | Acta Crystallogr F Struct Biol Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5287368/ https://ncbi.nlm.nih.gov/pubmed/28045392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16020070 |
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