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Capture of an intermediate in the catalytic cycle of l-aspartate-β-semialdehyde dehydrogenase

The structural analysis of an enzymatic reaction intermediate affords a unique opportunity to study a catalytic mechanism in extraordinary detail. Here we present the structure of a tetrahedral intermediate in the catalytic cycle of aspartate-β-semialdehyde dehydrogenase (ASADH) from Haemophilus inf...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Blanco, Julio, Moore, Roger A., Viola, Ronald E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240666/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14559965/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1634958100
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