Loss of maternal Trim28 causes male-predominant early embryonic lethality

Global DNA demethylation is a hallmark of embryonic epigenetic reprogramming. However, embryos engage noncanonical DNA methylation maintenance mechanisms to ensure inheritance of exceptional epigenetic germline features to the soma. Besides the paradigmatic genomic imprints, these exceptions remain...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Sampath Kumar, Abhishek, Seah, Michelle K.Y., Ling, Ka Yi, Wang, Yaju, Tan, Joel H.L., Nitsch, Sandra, Lim, Shu Ly, Lorthongpanich, Chanchao, Wollmann, Heike, Low, Diana H.P., Guccione, Ernesto, Messerschmidt, Daniel M.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Research Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287108/
https://ncbi.nlm.nih.gov/pubmed/28115466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.291195.116
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