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Current insights into LMNA cardiomyopathies: Existing models and missing LINCs

The nuclear lamina is a critical structural domain for the maintenance of genomic stability and whole-cell mechanics. Mutations in the LMNA gene, which encodes nuclear A-type lamins lead to the disruption of these key cellular functions, resulting in a number of devastating diseases known as laminop...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Brayson, Daniel, Shanahan, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287098/
https://ncbi.nlm.nih.gov/pubmed/28125396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1260798
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