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Reactivation of autophagy ameliorates LMNA cardiomyopathy

Mutations in the LMNA gene, which encodes lamin A and C (lamin A/C), cause a diverse spectrum of tissue-selective diseases termed laminopathies. The most prevalent form affects striated muscles as dilated cardiomyopathy with variable skeletal muscle involvement, which includes autosomal Emery-Dreifu...

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Detalhes bibliográficos
Main Authors: Choi, Jason C., Worman, Howard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542212/
https://ncbi.nlm.nih.gov/pubmed/23044536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22403
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