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Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence

Cancer cells with stem-like properties are believed to contribute to treatment resistance, dissemination, and recurrence. SOX9 controls stem cell plasticity and its deregulation may provide a basis for tumor progression. Here, we summarize our findings of targeted SOX9 destruction by SCF(FBW7) (Skp1...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Oncol
Asıl Yazarlar: Suryo Rahmanto, Aldwin, Swartling, Fredrik J., Sangfelt, Olle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286959/
https://ncbi.nlm.nih.gov/pubmed/28197531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1252871
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