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Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence
Cancer cells with stem-like properties are believed to contribute to treatment resistance, dissemination, and recurrence. SOX9 controls stem cell plasticity and its deregulation may provide a basis for tumor progression. Here, we summarize our findings of targeted SOX9 destruction by SCF(FBW7) (Skp1...
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| Veröffentlicht in: | Mol Cell Oncol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286959/ https://ncbi.nlm.nih.gov/pubmed/28197531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1252871 |
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