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Effect of HIV-1 Env on SERINC5 Antagonism

SERINC5 is able to restrict HIV-1 infection by drastically impairing the infectivity of viral particles. Studies have shown that the HIV-1 Nef protein counters SERINC5 through downregulating SERINC5 from the cell surface and preventing the virion incorporation of SERINC5. In addition, the Env protei...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Beitari, Saina, Ding, Shilei, Pan, Qinghua, Finzi, Andrés, Liang, Chen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286904/
https://ncbi.nlm.nih.gov/pubmed/27928004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02214-16
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