Inhibition of an Aquatic Rhabdovirus Demonstrates Promise of a Broad-Spectrum Antiviral for Use in Aquaculture

Many enveloped viruses cause devastating disease in aquaculture, resulting in significant economic impact. LJ001 is a broad-spectrum antiviral compound that inhibits enveloped virus infections by specifically targeting phospholipids in the lipid bilayer via the production of singlet oxygen ((1)O(2))...

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Bibliographic Details
Published in:J Virol
Main Authors: Balmer, Bethany F., Powers, Rachel L., Zhang, Ting-Hu, Lee, Jihye, Vigant, Frederic, Lee, Benhur, Jung, Michael E., Purcell, Maureen K., Snekvik, Kevin, Aguilar, Hector C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286899/
https://ncbi.nlm.nih.gov/pubmed/27903801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02181-16
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