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The Rigid Amphipathic Fusion Inhibitor dUY11 Acts through Photosensitization of Viruses

Rigid amphipathic fusion inhibitors (RAFIs) are lipophilic inverted-cone-shaped molecules thought to antagonize the membrane curvature transitions that occur during virus-cell fusion and are broad-spectrum antivirals against enveloped viruses (Broad-SAVE). Here, we show that RAFIs act like membrane-...

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Detalhes bibliográficos
Main Authors: Vigant, Frederic, Hollmann, Axel, Lee, Jihye, Santos, Nuno C., Jung, Michael E., Lee, Benhur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911596/
https://ncbi.nlm.nih.gov/pubmed/24284320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02907-13
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