Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses

Antiviral drugs targeting viral proteins often result in prompt selection for resistance. Moreover, the number of viral targets is limited. Novel antiviral targets are therefore needed. The unique characteristics of fusion between virion envelopes and cell membranes may provide such targets. Like al...

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Main Authors: St.Vincent, Mireille R., Colpitts, Che C., Ustinov, Alexey V., Muqadas, Muhammad, Joyce, Michael A., Barsby, Nicola L., Epand, Raquel F., Epand, Richard M., Khramyshev, Stanislav A., Valueva, Olga A., Korshun, Vladimir A., Tyrrell, D. Lorne J., Schang, Luis M.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2010
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951442/
https://ncbi.nlm.nih.gov/pubmed/20823220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010026107
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