Histidine 375 Modulates CD4 Binding in HIV-1 CRF01_AE Envelope Glycoproteins

The envelope glycoproteins (Envs) from human immunodeficiency virus type 1 (HIV-1) mediate viral entry. The binding of the HIV-1 gp120 glycoprotein to CD4 triggers conformational changes in gp120 that allow high-affinity binding to its coreceptors. In contrast to all other Envs from the same phyloge...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Zoubchenok, Daria, Veillette, Maxime, Prévost, Jérémie, Sanders-Buell, Eric, Wagh, Kshitij, Korber, Bette, Chenine, Agnès L., Finzi, Andrés
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286895/
https://ncbi.nlm.nih.gov/pubmed/27928014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02151-16
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