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Histidine 375 Modulates CD4 Binding in HIV-1 CRF01_AE Envelope Glycoproteins
The envelope glycoproteins (Envs) from human immunodeficiency virus type 1 (HIV-1) mediate viral entry. The binding of the HIV-1 gp120 glycoprotein to CD4 triggers conformational changes in gp120 that allow high-affinity binding to its coreceptors. In contrast to all other Envs from the same phyloge...
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| 發表在: | J Virol |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286895/ https://ncbi.nlm.nih.gov/pubmed/27928014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02151-16 |
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