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Optimal knockout strategies in genome-scale metabolic networks using particle swarm optimization

BACKGROUND: Knockout strategies, particularly the concept of constrained minimal cut sets (cMCSs), are an important part of the arsenal of tools used in manipulating metabolic networks. Given a specific design, cMCSs can be calculated even in genome-scale networks. We would however like to find not...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Nair, Govind, Jungreuthmayer, Christian, Zanghellini, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286819/
https://ncbi.nlm.nih.gov/pubmed/28143607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1483-5
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