Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells

BACKGROUND: The initiation and progression of malignant tumors is driven by distinct subsets of tumor-initiating or cancer stem-like cells (CSCs) which develop therapy/apoptosis resistance and self-renewal capacity. In order to be able to eradicate these CSCs with novel classes of anti-cancer therap...

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Publicado en:Mol Cancer
Autores principales: Melzer, Catharina, von der Ohe, Juliane, Lehnert, Hendrik, Ungefroren, Hendrik, Hass, Ralf
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286787/
https://ncbi.nlm.nih.gov/pubmed/28148265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0595-x
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