Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin

BACKGROUND: Translationally controlled tumour protein TCTP is an anti-apoptotic protein frequently overexpressed in cancers, where high levels are often associated with poor patient outcome. TCTP may be involved in protecting cancer cells against the cytotoxic action of anti-cancer drugs. Here we st...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Commun Signal
Prif Awduron: Bommer, Ulrich-Axel, Vine, Kara L., Puri, Prianka, Engel, Martin, Belfiore, Lisa, Fildes, Karen, Batterham, Marijka, Lochhead, Alistair, Aghmesheh, Morteza
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286767/
https://ncbi.nlm.nih.gov/pubmed/28143584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0164-3
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