The E3 ubiquitin ligase RNF114 and TAB1 degradation are required for maternal‐to‐zygotic transition

The functional role of the ubiquitin‐proteasome pathway during maternal‐to‐zygotic transition (MZT) remains to be elucidated. Here we show that the E3 ubiquitin ligase, Rnf114, is highly expressed in mouse oocytes and that knockdown of Rnf114 inhibits development beyond the two‐cell stage. To study...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Yang, Ye, Zhou, Cheng, Wang, Ying, Liu, Weixiao, Liu, Chao, Wang, Liying, Liu, Yujiao, Shang, Yongliang, Li, Mingrui, Zhou, Shuai, Wang, Yuanting, Zeng, Wentao, Zhou, Jianli, Huo, Ran, Li, Wei
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286393/
https://ncbi.nlm.nih.gov/pubmed/28073917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642573
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