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HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma

Loss of primary cilia is frequently observed in tumor cells, including pancreatic ductal adenocarcinoma (PDAC) cells, suggesting that the absence of this organelle may promote tumorigenesis through aberrant signal transduction and the inability to exit the cell cycle. However, the molecular mechanis...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Kobayashi, Tetsuo, Nakazono, Kosuke, Tokuda, Mio, Mashima, Yu, Dynlacht, Brian David, Itoh, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286357/
https://ncbi.nlm.nih.gov/pubmed/28028031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541922
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