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Triple helix formation inhibits transcription elongation in vitro.

We have identified a 15-nucleotide site within a G-free transcription cassette that forms triple helix with sequence-specific oligodeoxyribonucleotides. When oligodeoxynucleotides were added to template DNA prior to in vitro transcription, a significant fraction of transcripts were truncated at a si...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Young, S L, Krawczyk, S H, Matteucci, M D, Toole, J J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52859/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946419/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.10023
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