Long‐chain acyl‐CoA synthetase 6 regulates lipid synthesis and mitochondrial oxidative capacity in human and rat skeletal muscle

KEY POINTS: Long‐chain acyl‐CoA synthetase 6 (ACSL6) mRNA is present in human and rat skeletal muscle, and is modulated by nutritional status: exercise and fasting decrease ACSL6 mRNA, whereas acute lipid ingestion increase its expression. ACSL6 genic inhibition in rat primary myotubes decreased lip...

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Bibliographic Details
Published in:J Physiol
Main Authors: Teodoro, Bruno G., Sampaio, Igor H., Bomfim, Lucas H. M., Queiroz, André L., Silveira, Leonardo R., Souza, Anderson O., Fernandes, Anna M. A. P., Eberlin, Marcos N., Huang, Tai‐Yu, Zheng, Donghai, Neufer, P. Darrell, Cortright, Ronald N., Alberici, Luciane C.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Muscle
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285616/
https://ncbi.nlm.nih.gov/pubmed/27647415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272962
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